The A5 was closed northbound between the Whittington and the Gobowen roundabouts following the accident at 10.22am.
Emergency services said the bike had hit a barrier along the busy trunk road, which also carries the A483.
The rider was airlifted by air ambulance to the Royal Stoke Hospital.
RTC on the A5 / A483 at Gobowen R/A. Road closed North bound from Whittington R/A and South bound. Diversion through Whittington village.— Oswestry SNT (@OsCops) March 11, 2020
A spokesman for the ambulance service said:
“We were called at 10.22am to reports of a collision at the junction of the B5069 and the A5 involving a motorbike and barrier.
"We sent the Midlands Air Ambulance from Cosford, a land ambulance and paramedic officer to the scene. We treated one patient, a man, who was the motorcyclist for potentially serious injuries.
"He was taken to Royal Stoke Hospital by air ambulance for further treatment.”
Traffic was diverted though Whittington and Gobowen.