Mark Millar and designer Gabrielle Blackman from DIY SOS have been at the youngster's family's home in Trench, Telford, getting it ready for the Big Build at the end of the month.
The BBC team is there to help transform the house so Matthew can return home for the first time in more than a year and a half. Mr Millar said he was amazed at how the community in Telford had got behind Matthew's cause and said they couldn't wait to get started.
The team held a trades day yesterday, where everyone who had applied to help went to the house to see the plans and find out what would be needed when the build begins on February 28.
Mr Millar said: "It has been a great response. We've been at the house all day and we have had hundreds of people turn up. They've all turned up, asked what we needed and agreed to give up 10 days of their time to help us.
"A lot of the people have already donated and have turned out again to give up their time.
"I can't wait to get started. Who wouldn't want to be a part of something where people are so enthusiastic? It is going to be fun, excitement and tears."
Matthew, who is now 11, has been cared for at Birmingham Children's Hospital since August 2015 after he was diagnosed with brain and spinal cancer.
After more than a year in hospital, Matthew has finished his chemotherapy and since the end of last year has been living in a rented house until the family home is made suitable for his needs.
Over the past year, Wrockwardine Wood Junior School and the wider community have managed to raise hundreds of thousands of pounds towards renovating Matthew's Trench home for when he is well enough to be discharged from hospital.
Now that DIY SOS has stepped in, the money will be used by his parents Sue and Leigh to help fund his ongoing treatment.
Mr Millar said they have filled all of their requirements for the build but would urge people who can supply things like timber, roof tiles, plumbing and electrical materials to come forward.