A yellow weather warning is in place with the Met Office advising delays to road, rail, air and ferry transport are likely.
The majority of the country, and the whole of Shropshire and Mid Wales, is included in the warning.
Temperatures in some places are set to dip around 3C (37F) during the warning, but could feel like -2 (28F).
Very strong winds are due to hit northern areas of Scotland first from noon on Friday, with the weather front gradually making its way further south.
The Met Office said gusts are likely to reach 50mph to 60mph widely, but could reach 70mph to 80mph in coastal areas.
Bridges and roads could also close and the Met Office said there is a slight chance power cuts may occur, affecting services such as mobile phone coverage.
The strong winds are set to affect the majority of the UK, with only a small part of south-east England avoiding a yellow weather warning.
The warning will be in place until 6pm on Saturday.