The work will start on the busy Sundorne Road to the north west of the town on January 25. It is expected to last five days.
Improvements are to be made to the road markings and traffic signs at the mini-roundabout outside the medical centre as part of a £1.25m programme of work being carried out by Shropshire Council and its contractors.
It was originally scheduled to be carried out last October, but was postponed due to the presences of a gas main at the site.
Work will be carried out between 9.30am and 4pm each day, and the road will be closed during these times.
The mini-roundabout will be reshaped, and the illuminated traffic signs repositioned.
Other existing signs will be replaced and new signs put up at new locations.
Road workings will also be replaced or refreshed on the approach to the roundabout and also along the length of Sundorne Road, from Heathgates roundabout to the A49.
Shropshire Council says a signed diversion route will be place when the road is closed and access to properties and businesses, and for emergency vehicles, will be maintained at all times.
"We thank residents, businesses and road users for their understanding while this important work is carried out," a council spokesman said.
The work – funded through integrated transport capital funding – is one of 14 road safety schemes being carried out across the county between April 2020 and March 2021.