Bloor Homes has made a reserved matters application for permission for its scheme south of the Springfield Industrial Estate off Springfield Road in Newport.
The proposal also includes "associated open space, infrastructure works and access of Station Road".
A statement on behalf of Bloor Homes said the site would represent "high-quality legible development and attractive place to live".
An existing pond and veteran oak tree will be retained as part of the development.
"Open space located in the northern area of the site will reinforce site boundaries with native tree and shrub buffer planting containing holly for year-round screening combined with meadow and wildlife grassland which will enhance biodiversity and increase wildlife value into the public open space.
"A significant number of trees and hedgerows are being retained/being replaced to enclose the development in this urban fringe location. The claimed pedestrian route is being retained with a slight diversion."
A number of Newport residents have voiced their objections.
Mrs Lynn Doble wrote: "If this development was to be built, it would make crime more attractive due to the access by road onto the bypass as well as the felling of trees, exposing more places for people to commit crime. Crimes have already been reported to the police in relation to this area of Newport.
"Furthermore, Newport no longer has a police station (as it has now been turned into housing) and the lack of police presence in the area has posed an issue for some time.
"There are so many better uses for the land which would help support nature, reduce pollution and would encourage the community to engage in exercise, wellbeing projects and to stop Newport from being destroyed by over-development."
Meanwhile Mrs Zhan Lu Smith said she objected because of the impact on the natural environment.
"The area affected is a pleasant wooded space ideal for families with children to explore nature, for strolling, walking their dogs safely, and undertaking outdoor pursuits without general and traffic noise and air pollution. Bird life will be disturbed by the loss of trees, as will other wild life such as squirrels, rabbits and hedgehogs.
"I believe the increased population density will also adversely affect the character of the area. There will be greater use of facilities such as doctors and dentists, which are already at a premium.
"I often cycle along the footpath through the woods, stop to look and wonder at wild flowers, and I will be extremely devastated at their loss. The flowers (and the wildlife) are an extremely important part of the ecosystem.
"In the present viral situation it is even more important to have a space where one can be with nature. It is madness to even consider cutting down these established forest trees."
Mr Darren Pamplin wrote: "Building these estates has a knock-on effect and already in Newport the schools are over-subscribed, getting a doctors appointment is nigh on impossible. The council need to identify the level of sustainability and address the real effect these developments have on such a small town."