Pensioner John Morris says he has won support from across Europe as well as in the United States.
The 77-year-old has described plans to demolish the landmark towers as “sacrilege”.
He says he has had the signatures of the Munro family from Houston, Texas, as well as Ray and Gill Cook and Andrew and Caroline Black from Roville in France.
The Munros attached a comment to their signature, saying: “We love visiting Ironbridge when we are in the UK and the towers are a unique part of the landscape.”
Mr Morris, from Gnosall, started collecting signatures in November after it was announced by the station’s owner Uniper that the site, including the iconic pink cooling towers, had been earmarked for demolition.
The process of taking down the towers with controlled detonations is due to begin proper in Spring 2018.
Mr Morris said he was determined to put a stop to the plans by persuading the company to look at other options. He said: “They’re going to need two years and two million pounds to knock them down – why not spend a million and make it into a visitor’s attraction? Those towers are a part of Ironbridge history.
“We might not win but we have to try.”
Mr Morris maintains the towers would make an ideal attraction, with a railway set up to take people on tours of the station.
He estimates his handwritten petition to save the towers now has 350 signatures.
Plans for the main demolition of Shropshire’s landmark power station have now been approved by Shropshire Council.
Full demolition of the main power station site is set to begin in spring 2018 and will include the removal of all the buildings that have come to the end of their operational life.
The work is expected to take about 36 months and it is anticipated that the site’s iconic pink cooling towers will be demolished at a date not yet revealed using controlled detonation.
Gill Dickinson, a spokeswoman for power station owners Uniper, said the company was looking forward to “starting the journey to bring forward the site’s future redevelopment”.
A shropshirestar.com poll revealed that there was support for the towers to be kept.
While 35 per cent sent the site should be flattened and returned to nature, the majority of those questioned supported options that would retain the cooling towers.