West Midlands Ambulance Service said that four people were injured in the crash on the A4169 near Much Wenlock – with the girl being the most severely hurt.
The crash took place at around 5.48pm on Tuesday, October 5.
In total three ambulances, a paramedic officer and the Midlands Air Ambulance from Cosford attended.
A spokesman for West Midlands Ambulance Service: "On arrival, we found five patients.
"The first patient, a girl, a passenger in one of the cars, had sustained potentially serious injuries. She received treatment from ambulance staff at the scene and was conveyed to Alder Hey Hospital for further treatment.
"The second patient, a girl, a passenger in one of the cars, was assessed and had sustained injuries not considered to be serious.
"The third and fourth patients, both women who were drivers of two of the cars, were assessed on scene and had sustained injuries considered to be minor.
"All three were conveyed to Royal Shrewsbury Hospital for further assessment. A child was also assessed and was not injured."
West Mercia Police said they had attended the incident with a spokesman adding: "We were called at 5.43pm to an RTC on the A4169 involving three vehicles. A six year old child was taken to hospital with serious injuries, her injuries are not believed to be life-threatening. The road was closed for a short time."